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Clinical Medicine
Scientific Show Stopper
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238 Posts
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Deriving hypothalamic-like neurons
Liheng Wang and colleagues reveal that hypothalamic-like neurons can be derived from human pluripotent stem cells….
Published January 2, 2015
Scientific Show Stopper
Stem cells
Breaking up with glutamine
Courtney Karner and colleagues reveal that WNT signaling mediates bone anabolism through increasing catabolism of glutamine…
Published December 22, 2014
Scientific Show Stopper
Bone biology
L cells to the rescue
Natalia Peterson and colleagues demonstrate that increasing L cell populations in the gut improves insulin responses and glucose tolerance in a murine type 2 diabetes model…
Published December 15, 2014
Scientific Show Stopper
Endocrinology
T cell signals substitute for EBV oncoprotein
Shi-Dong Ma and colleagues develop a human cord blood-based model of EBV-induced B cell lymphoma to evaluate the requirement of EBV oncoprotein LMP1 in pathogenesis…
Published December 8, 2014
Scientific Show Stopper
Oncology
Risk factor for renal allograft fibrosis
Madhav Menon and colleagues reveal that SHROOM3 expression in renal allografts promotes fibrosis and increases allograft failure…
Published December 1, 2014
Scientific Show Stopper
Nephrology
Delivering protection for photoreceptors
Leah Byrne and colleagues reveal that the 2 isoforms of rod-derived cone viability factor differentially protect rod and cone photoreceptors…
Published November 21, 2014
Scientific Show Stopper
Ophthalmology
The regenerating liver
Claus Kordes and colleagues demonstrate that hepatic stellate cells contribute to liver regeneration…
Published November 17, 2014
Scientific Show Stopper
Hepatology
Protection against preterm labor
Yucel Akgul and colleagues reveal that the glycosaminoglycan hyaluronan is necessary for barrier function in the lower reproductive tract and protects against pathogen-induced preterm birth...
Published November 10, 2014
Scientific Show Stopper
Reproductive biology
Translating mechanical stress to fibrogenesis
Shaik Rahaman and colleagues reveal that TRPV4 channel activity links mechanical stress and pulmonary fibrosis…
Published November 3, 2014
Scientific Show Stopper
Pulmonology
Good guys and bad guys
Emilie Degagné and colleagues reveal that sphingolipid metabolism influences inflammatory pathways and tumorigenic transformation in the intestine…
Published October 27, 2014
Scientific Show Stopper
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