During chronic infection of the cystic fibrosis (CF) lung, Pseudomonas aeruginosa grows
and persists in a microaerobic to anaerobic environment. P. aeruginosa is well adapted to
thrive under such conditions and contains multiple enzyme systems for energy generation
under oxygen-restricted or even anaerobic conditions. Recent data confirm a
heterogeneous environment in the CF lung and indicate that P. aeruginosa induces enzyme
systems for microaerobic growth but also denitrification and fermentative pathways …