Carbohydrate and lipid metabolism of the renal tubule in diabetes mellitus
WG Guder, M Schmolke… - European journal of clinical …, 1992 - degruyter.com
WG Guder, M Schmolke, G Wirthensohn
European journal of clinical chemistry and clinical biochemistry, 1992•degruyter.comDiabetic nephropathy not only involves vascular and glomerular changes but also affects
tubular metabolism, structure and function. Under acute insulin withdrawal the tubular size
increases with glomerular hyperfiltration. Insulin like growth factor l (IGF1) has been found to
be a candidate mediator involved under these conditions.
tubular metabolism, structure and function. Under acute insulin withdrawal the tubular size
increases with glomerular hyperfiltration. Insulin like growth factor l (IGF1) has been found to
be a candidate mediator involved under these conditions.
Summary
Diabetic nephropathy not only involves vascular and glomerular changes but also affects tubular metabolism, structure and function. Under acute insulin withdrawal the tubular size increases with glomerular hyperfiltration. Insulin like growth factor l (IGF1) has been found to be a candidate mediator involved under these conditions.
De Gruyter