Carboplatin-based chemoradiotherapy in advanced cervical cancer: an alternative to cisplatin-based regimen?
AM Sebastião, LS da Silva Rocha, RD Gimenez… - European Journal of …, 2016 - Elsevier
Objective To evaluate the results of treatment with cisplatin or carboplatin concomitant with
radiotherapy (RT) in cases of locally advanced cervical cancer (CC). Methods This study is a
retrospective analysis of medical records of 184 patients with cervical cancer stage IIB-IVA
who were treated at Instituto do Câncer do Estado de São Paulo from May 2008 to
December 2012. All patients received complete pelvic region external-beam RT with weekly
cisplatin (cis-RT, 40 mg/m 2; n= 159) or carboplatin (carbo-RT, AUC 2; n= 25), followed by …
radiotherapy (RT) in cases of locally advanced cervical cancer (CC). Methods This study is a
retrospective analysis of medical records of 184 patients with cervical cancer stage IIB-IVA
who were treated at Instituto do Câncer do Estado de São Paulo from May 2008 to
December 2012. All patients received complete pelvic region external-beam RT with weekly
cisplatin (cis-RT, 40 mg/m 2; n= 159) or carboplatin (carbo-RT, AUC 2; n= 25), followed by …