[PDF][PDF] New anti-cancer strategies: epigenetic therapies and biomarkers
C Balch, JS Montgomery, HI Paik, S Kim, TH Huang… - Front Biosci, 2005 - academia.edu
Introduction 3. Epigenetic Modifications in Cancer 3.1. DNA methylation 3.2. Histone
deacetylation and methylation 3.3. Epigenetic aberrations in drug resistance 4. Current
epigenetic therapies for cancer 4.1. DNA methylation inhibitors 4.2. Histone deacetylase
inhibitors 4.3. Combined methylation/HDAC inhibition. 5. Epigenetic resensitization and
immunotherapy 6. Potential detrimental effects of epigenetic therapies 7. Analytical methods
for epigenetic biomarker discovery 7.1. Global and high-throughput analyses 7.2. Epigenetic …
deacetylation and methylation 3.3. Epigenetic aberrations in drug resistance 4. Current
epigenetic therapies for cancer 4.1. DNA methylation inhibitors 4.2. Histone deacetylase
inhibitors 4.3. Combined methylation/HDAC inhibition. 5. Epigenetic resensitization and
immunotherapy 6. Potential detrimental effects of epigenetic therapies 7. Analytical methods
for epigenetic biomarker discovery 7.1. Global and high-throughput analyses 7.2. Epigenetic …
Abstract
Introduction 3. Epigenetic Modifications in Cancer 3.1. DNA methylation 3.2. Histone deacetylation and methylation 3.3. Epigenetic aberrations in drug resistance 4. Current epigenetic therapies for cancer 4.1. DNA methylation inhibitors 4.2. Histone deacetylase inhibitors 4.3. Combined methylation/HDAC inhibition. 5. Epigenetic resensitization and immunotherapy 6. Potential detrimental effects of epigenetic therapies 7. Analytical methods for epigenetic biomarker discovery 7.1. Global and high-throughput analyses 7.2. Epigenetic biomarkers 7.3 Bioinformatical analyses 8. Conclusions 9. Acknowledgments 10. References
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