The role of glucagon in the pathophysiology and management of diabetes
GR Kulina, EJ Rayfield - Endocrine practice, 2016 - Elsevier
Objective: There is general recognition that insulin and glucagon are the main hormones
involved in the pathophysiology of diabetes, but the role of glucagon in diabetes is complex
and in some circumstances controversial. The increasing appreciation of the role of
glucagon in currently used hypoglycemic agents and the ongoing development of glucagon-
targeted therapies underscores glucagon's important contribution in optimizing diabetes
management. The current review provides a background on glucagon physiology and …
involved in the pathophysiology of diabetes, but the role of glucagon in diabetes is complex
and in some circumstances controversial. The increasing appreciation of the role of
glucagon in currently used hypoglycemic agents and the ongoing development of glucagon-
targeted therapies underscores glucagon's important contribution in optimizing diabetes
management. The current review provides a background on glucagon physiology and …