[HTML][HTML] Presence of hyaluronan in lung alveoli in severe Covid-19: An opening for new treatment options?

U Hellman, MG Karlsson, A Engström-Laurent… - Journal of Biological …, 2020 - ASBMB
Severe coronavirus disease 2019 (Covid-19) is characterized by inflammation of the lungs
with increasing respiratory impairment. In fatal Covid-19, lungs at autopsy have been filled
with a clear liquid jelly. However, the nature of this finding has not yet been determined. The
aim of the study was to demonstrate whether the lungs of fatal Covid-19 contain hyaluronan,
as it is associated with inflammation and acute respiratory distress syndrome (ARDS) and
may have the appearance of liquid jelly. Lung tissue obtained at autopsy from three …