Systemic inflammation in nonalcoholic fatty liver disease is characterized by elevated levels of CCL2
JW Haukeland, JK Damås, Z Konopski, EM Løberg… - Journal of …, 2006 - Elsevier
BACKGROUND/AIMS: To elucidate the role of systemic inflammation in nonalcoholic fatty
liver disease (NAFLD). METHODS: Serum samples in 47 patients with histologically verified
NAFLD (22 with simple steatosis and 25 with nonalcoholic steatohepatitis [NASH]), and in
30 age-, sex-and ethnicity-matched healthy controls, were assessed for (i) general markers
of inflammation (C-reactive protein [CRP], tumor necrosis factor [TNF]-α, and interleukin [IL]-
6),(ii) chemokines (CC-chemokine ligand [CCL] 2/monocyte chemoattractant protein [MCP] …
liver disease (NAFLD). METHODS: Serum samples in 47 patients with histologically verified
NAFLD (22 with simple steatosis and 25 with nonalcoholic steatohepatitis [NASH]), and in
30 age-, sex-and ethnicity-matched healthy controls, were assessed for (i) general markers
of inflammation (C-reactive protein [CRP], tumor necrosis factor [TNF]-α, and interleukin [IL]-
6),(ii) chemokines (CC-chemokine ligand [CCL] 2/monocyte chemoattractant protein [MCP] …