The αvβ6 integrin is a highly specific immunohistochemical marker for cholangiocarcinoma
E Patsenker, L Wilkens, V Banz, CH Österreicher… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC)
are common primary hepatic malignancies. Their immunohistological differentiation using
specific markers is pivotal for treatment and prognosis. We found αvβ6 integrin strongly
upregulated in biliary fibrosis, but its expression in primary and secondary liver tumours is
unknown. Here, we aimed to evaluate the diagnostic applicability of αvβ6 integrin in
differentiating primary liver cancers. METHODS: Expression of αvβ6 integrin was evaluated …
are common primary hepatic malignancies. Their immunohistological differentiation using
specific markers is pivotal for treatment and prognosis. We found αvβ6 integrin strongly
upregulated in biliary fibrosis, but its expression in primary and secondary liver tumours is
unknown. Here, we aimed to evaluate the diagnostic applicability of αvβ6 integrin in
differentiating primary liver cancers. METHODS: Expression of αvβ6 integrin was evaluated …