Non-alcoholic fatty liver disease–a global public health perspective

ZM Younossi - Journal of hepatology, 2019 - Elsevier
As the epidemics of obesity and type 2 diabetes mellitus increase worldwide, the prevalence
of non-alcoholic fatty liver disease (NAFLD) is increasing proportionately. The subtype of
NAFLD which can be characterised as non-alcoholic steatohepatitis (NASH) is a potentially
progressive liver disease that can lead to cirrhosis, hepatocellular carcinoma, liver
transplantation, and death. NAFLD is also associated with extrahepatic manifestations such
as chronic kidney disease, cardiovascular disease and sleep apnoea. NAFLD and NASH …