Metabolic responses to 20 days of overeating were examined in five healthy volunteers.
Overfeeding caused a variable increase (1–18%) in basal metabolic rate but no change in
metabolic rate during light exercise. Postprandial resting metabolic rate was 8–40% higher
(mean 18%) during overeating. The increase in oxygen consumption during a
norepinephrine infusion was the same before (20±2%) and after (17±3%) overfeeding.
Overfeeding elevated basal insulin concentrations in all subjects and increased the insulin …