[HTML][HTML] Identification and characterization of RBEL1 subfamily of GTPases in the Ras superfamily involved in cell growth regulation
JA Montalbano, K Lui, MS Sheikh, Y Huang - Journal of biological chemistry, 2009 - ASBMB
Recently, we reported the identification of a novel gene named RBEL1 (Rab-like protein 1)
and characterized its two encoded isoforms, RBEL1A and RBEL1B, that function as novel
GTPases of Ras superfamily. Here we report the identification of two additional splice
variants of RBEL1 that we have named RBEL1C and-D. All four RBEL1 isoforms (A, B, C,
and D) have identical N termini harboring the Rab-like GTPase domains but contain variable
C termini. Although all isoforms can be detected in both cytoplasm and nucleus, RBEL1A is …
and characterized its two encoded isoforms, RBEL1A and RBEL1B, that function as novel
GTPases of Ras superfamily. Here we report the identification of two additional splice
variants of RBEL1 that we have named RBEL1C and-D. All four RBEL1 isoforms (A, B, C,
and D) have identical N termini harboring the Rab-like GTPase domains but contain variable
C termini. Although all isoforms can be detected in both cytoplasm and nucleus, RBEL1A is …
