Aortic valve replacement should be operated on before symptom onset
BA Carabello - Circulation, 2012 - Am Heart Assoc
BA Carabello
Circulation, 2012•Am Heart Assoc112 this definition is sensitive but less specific for critical AS. Yet almost all would agree that
AVR is not indicated in asymptomatic patients unless AS is truly life-threatening. Thus, for
the purposes of this discussion, severe AS is defined as it was in the recent landmark
randomized trial of transcatheter AVR4 as a valve area 0.8 cm2. Although this is obviously
arbitrary, so is the aortic valve area of 1.0 cm2, and the smaller valve area shifts the risk-
benefit ratio further toward benefit for AVR, because the risk of waiting is higher.
AVR is not indicated in asymptomatic patients unless AS is truly life-threatening. Thus, for
the purposes of this discussion, severe AS is defined as it was in the recent landmark
randomized trial of transcatheter AVR4 as a valve area 0.8 cm2. Although this is obviously
arbitrary, so is the aortic valve area of 1.0 cm2, and the smaller valve area shifts the risk-
benefit ratio further toward benefit for AVR, because the risk of waiting is higher.
112 this definition is sensitive but less specific for critical AS. Yet almost all would agree that AVR is not indicated in asymptomatic patients unless AS is truly life-threatening. Thus, for the purposes of this discussion, severe AS is defined as it was in the recent landmark randomized trial of transcatheter AVR4 as a valve area 0.8 cm2. Although this is obviously arbitrary, so is the aortic valve area of 1.0 cm2, and the smaller valve area shifts the risk-benefit ratio further toward benefit for AVR, because the risk of waiting is higher.
Am Heart Assoc