Dissection of adult mouse utricle and adenovirus-mediated supporting-cell infection
CS Brandon, C Voelkel-Johnson, LA May… - JoVE (Journal of …, 2012 - jove.com
Hearing loss and balance disturbances are often caused by death of mechanosensory hair
cells, which are the receptor cells of the inner ear. Since there is no cell line that satisfactorily
represents mammalian hair cells, research on hair cells relies on primary organ cultures.
The best-characterized in vitro model system of mature mammalian hair cells utilizes organ
cultures of utricles from adult mice (Figure 1) 1-6. The utricle is a vestibular organ, and the
hair cells of the utricle are similar in both structure and function to the hair cells in the …
cells, which are the receptor cells of the inner ear. Since there is no cell line that satisfactorily
represents mammalian hair cells, research on hair cells relies on primary organ cultures.
The best-characterized in vitro model system of mature mammalian hair cells utilizes organ
cultures of utricles from adult mice (Figure 1) 1-6. The utricle is a vestibular organ, and the
hair cells of the utricle are similar in both structure and function to the hair cells in the …
