Increased insulin levels after OGTT load in peripheral blood and cerebrospinal fluid of patients with dementia of Alzheimer type
Y Fujisawa, K Sasaki, K Akiyama - Biological psychiatry, 1991 - Elsevier
An investigation was carried out to determine whether a disturbance of glycometabolism is
associated with dementia of Alzheimer type (AD). The first part of the study was carried out
on 108 AD patients and 57 normal controls (NCs). Neither the plasma level of insulin nor
that of glucose differed significantly between the two groups before the oral glucose
tolerance test (OGTT), whereas there was a significantly greater increase of the plasma
insulin in the AD group than in the NC group after the OGTT. The second part of the study …
associated with dementia of Alzheimer type (AD). The first part of the study was carried out
on 108 AD patients and 57 normal controls (NCs). Neither the plasma level of insulin nor
that of glucose differed significantly between the two groups before the oral glucose
tolerance test (OGTT), whereas there was a significantly greater increase of the plasma
insulin in the AD group than in the NC group after the OGTT. The second part of the study …
