Estrogen receptor-β regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice
M Nomura, E McKenna, KS Korach, DW Pfaff… - Molecular brain …, 2002 - Elsevier
Estrogen receptor (ER)-β, unlike ER-α, is localized in the hypothalamic paraventricular
nucleus (PVN) which also contains neuropeptide synthesizing neurons, such as oxytocin
(OT), arginine vasopressin (AVP) and corticotropin-releasing hormone (CRH). Although it is
known that some ER-β containing neurons co-express OT and AVP, but not CRH, in the
PVN, it is not yet determined whether ER-β activation may indeed play a role in estrogenic
regulation on syntheses of these neuropeptides. In the present study, we tested this …
nucleus (PVN) which also contains neuropeptide synthesizing neurons, such as oxytocin
(OT), arginine vasopressin (AVP) and corticotropin-releasing hormone (CRH). Although it is
known that some ER-β containing neurons co-express OT and AVP, but not CRH, in the
PVN, it is not yet determined whether ER-β activation may indeed play a role in estrogenic
regulation on syntheses of these neuropeptides. In the present study, we tested this …
