Polymorphism of the angiotensin-converting enzyme (ACE) gene in patients with thrombotic brain infarction
Y Doi, M Yoshinari, H Yoshizumi, S Ibayashi… - Atherosclerosis, 1997 - Elsevier
The relationship between cerebrovascular disease and an insertion/deletion (I/D)
polymorphism in intron 16 of the angiotensin-converting enzyme (ACE) gene is still being
debated. We examined its role as a risk factor in patients with thrombotic brain infarction.
The association between ACE gene polymorphism and ischemic stroke was examined in
181 patients with thrombotic brain infarction and 271 controls without strokes. The I/D
polymorphism was examined using the polymerase chain reaction. Distributions of the ACE …
polymorphism in intron 16 of the angiotensin-converting enzyme (ACE) gene is still being
debated. We examined its role as a risk factor in patients with thrombotic brain infarction.
The association between ACE gene polymorphism and ischemic stroke was examined in
181 patients with thrombotic brain infarction and 271 controls without strokes. The I/D
polymorphism was examined using the polymerase chain reaction. Distributions of the ACE …