Immune disorders of the liver and bile duct
JM Vierling - Gastroenterology Clinics of North America, 1992 - Elsevier
Several hepatobiliary diseases appear to be mediated by the host immune response. They
can be subdivided into those in which the immune reaction is against an infectious agent
such as hepatitis viruses, those in which the immune reaction appears to be against an
autoantigen expressed on hepatobiliary cells, and those due to alloimmunity. The existence
of autoimmune liver diseases indicates a breakdown in the mechanisms responsible for self-
tolerance. In HBV infection, the hepatocellular necrosis appears to be mediated by the host …
can be subdivided into those in which the immune reaction is against an infectious agent
such as hepatitis viruses, those in which the immune reaction appears to be against an
autoantigen expressed on hepatobiliary cells, and those due to alloimmunity. The existence
of autoimmune liver diseases indicates a breakdown in the mechanisms responsible for self-
tolerance. In HBV infection, the hepatocellular necrosis appears to be mediated by the host …