Expression of inducible nitric oxide synthase in paired neoplastic and non-neoplastic primary prostate cell cultures and prostatectomy specimen
J Wang, M Torbenson, Q Wang, JY Ro… - … Oncology: Seminars and …, 2003 - Elsevier
Nitric oxide (NO) is an important signaling molecule for ischemia, inflammation,
angiogenesis, immune response, and cell growth and differentiation. It has recently been
shown that increased production of NO within various human cancers may contribute to
tumor angiogenesis, tumor growth and metastasis, and tumor-related immune suppression.
NO can be produced by several NO synthases (NOS), including inducible synthase (iNOS),
which is expressed during cell activation and produces NO in larger quantity and for a …
angiogenesis, immune response, and cell growth and differentiation. It has recently been
shown that increased production of NO within various human cancers may contribute to
tumor angiogenesis, tumor growth and metastasis, and tumor-related immune suppression.
NO can be produced by several NO synthases (NOS), including inducible synthase (iNOS),
which is expressed during cell activation and produces NO in larger quantity and for a …
