Burkitt's lymphoma: new insights into molecular pathogenesis

C Bellan, S Lazzi, G De Falco, A Nyongo… - Journal of clinical …, 2003 - jcp.bmj.com
C Bellan, S Lazzi, G De Falco, A Nyongo, A Giordano, L Leoncini
Journal of clinical pathology, 2003jcp.bmj.com
The World Health Organisation classification reports three subcategories of Burkitt's
lymphoma (BL)—endemic, non-endemic, and immunodeficiency associated—proposed to
reflect the major clinical and genetic subtypes of this disease. These different types of BL
have been reviewed and studied by immunohistochemistry and molecular methods. The
results point out the heterogeneity of BL and suggest that AIDS related BL may have a
different pathogenesis from that of classic BL.
The World Health Organisation classification reports three subcategories of Burkitt’s lymphoma (BL)—endemic, non-endemic, and immunodeficiency associated—proposed to reflect the major clinical and genetic subtypes of this disease. These different types of BL have been reviewed and studied by immunohistochemistry and molecular methods. The results point out the heterogeneity of BL and suggest that AIDS related BL may have a different pathogenesis from that of classic BL.
jcp.bmj.com