Myeloperoxidase (MPO), a protein secreted by activated phagocytes, may be a potential
candidate for the generation of modified/oxidized lipoproteins in vivo via intermediate
formation of HOCl, a powerful oxidant. During the present study, the effects of reagent
NaOCl and OCl− generated by the MPO/H 2 O 2/Cl− system on physicochemical and
metabolic properties of high density lipoprotein (HDL) subclass 3 (HDL 3) were investigated.
Up to a molar oxidant: lipoprotein ratio of approximately 30: 1, apolipoprotein AI (apoA-I), the …