Glucose-2-t as a Tracer for Glucose Metabolism*
J Katz, A Dunn - Biochemistry, 1967 - ACS Publications
J Katz, A Dunn
Biochemistry, 1967•ACS PublicationsJ. Katzf and A. Dunn abstract: Glucose labeled both in position 2 with tritium and uniformly
with 14C (glucose-2-zU-14C) was injected into rats. The specific activity of blood glucose
and formation of labeled water were followed. The half-life of the tritium-labeled glucose was
found to be 22 min and that of 14C-labeled glucose, 34 min. Turnover of glucose calculated
from tritium data was 3% of the glucose pool/min, as compared to 2%/min from 14C data.
The z/, 4C ratios of liver glycogen isolated 80-120 min after injection were one-third to one …
with 14C (glucose-2-zU-14C) was injected into rats. The specific activity of blood glucose
and formation of labeled water were followed. The half-life of the tritium-labeled glucose was
found to be 22 min and that of 14C-labeled glucose, 34 min. Turnover of glucose calculated
from tritium data was 3% of the glucose pool/min, as compared to 2%/min from 14C data.
The z/, 4C ratios of liver glycogen isolated 80-120 min after injection were one-third to one …
J. Katzf and A. Dunn abstract: Glucose labeled both in position 2 with tritium and uniformly with 14C (glucose-2-zU-14C) was injected into rats. The specific activity of blood glucose and formation of labeled water were followed. The half-life of the tritium-labeled glucose was found to be 22 min and that of 14C-labeled glucose, 34 min.
Turnover of glucose calculated from tritium data was 3% of the glucose pool/min, as compared to 2%/min from 14C data. The z/, 4C ratios of liver glycogen isolated 80-120 min after injection were one-third to one-half of the mean z/14C ratio during the experi-
ACS Publications