Teratogenic compounds of Veratrum californicum (Durand). V. Comparison of cyclopian effects of steroidal alkaloids from the plant and structurally related …
RF Keeler, W Binns - Teratology, 1968 - Wiley Online Library
RF Keeler, W Binns
Teratology, 1968•Wiley Online LibraryCyclopamine, and its glycoside alkaloid X, along with jervine and veratrosine, induced
cyclopian malformations in offspring born to ewes ingesting these compounds on the
fourteenth day of gestation. Other steroidal alkaloids with somewhat similar structures and
various other steroidal compounds including certain hormones and steroidal sapogenins did
not induce the malformation.
cyclopian malformations in offspring born to ewes ingesting these compounds on the
fourteenth day of gestation. Other steroidal alkaloids with somewhat similar structures and
various other steroidal compounds including certain hormones and steroidal sapogenins did
not induce the malformation.
Abstract
Cyclopamine, and its glycoside alkaloid X, along with jervine and veratrosine, induced cyclopian malformations in offspring born to ewes ingesting these compounds on the fourteenth day of gestation. Other steroidal alkaloids with somewhat similar structures and various other steroidal compounds including certain hormones and steroidal sapogenins did not induce the malformation.
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