[HTML][HTML] Diminished gene expression of ileal apical sodium bile acid transporter explains impaired absorption of bile acid in patients with hypertriglyceridemia
WC Duane, LA Hartich, AE Bartman, SB Ho - Journal of lipid research, 2000 - ASBMB
Patients with type IV hyperlipoproteinemia, particularly those with familial
hypertriglyceridemia (FHT), have impaired absorption of bile acid, a defect that may
contribute to the hypertriglyceridemia (J. Lipid Res. 1995. 36: 96–107). To determine
whether this absorption defect is a result of abnormal expression of the ileal apical sodium
bile acid transporter (ASBT) gene, we biopsied the terminal ileum at colonoscopy in 28
subjects, 13 with hypertriglyceridemia and 15 control subjects. Of the 13 …
hypertriglyceridemia (FHT), have impaired absorption of bile acid, a defect that may
contribute to the hypertriglyceridemia (J. Lipid Res. 1995. 36: 96–107). To determine
whether this absorption defect is a result of abnormal expression of the ileal apical sodium
bile acid transporter (ASBT) gene, we biopsied the terminal ileum at colonoscopy in 28
subjects, 13 with hypertriglyceridemia and 15 control subjects. Of the 13 …