Assessment of the renin-angiotensin system in cirrhotic patients: comparison between plasma renin activity and direct measurement of immunoreactive renin

M Asbert, W Jiménez, J Gaya, P Ginés, V Arroyo… - Journal of …, 1992 - Elsevier
The renin-angiotensin system plays an important physiological role and has prognostic
significance in cirrhotics with ascites. The degree of stimulation of this system is usually
estimated by measuring plasma renin activity after incubation periods of 2–3 h. Recent
investigations showed that the direct measurement of immunoreactive renin also estimates
the degree of activity of the system. In this study, immunoreactive renin and plasma renin
activity (measured at incubation periods of 10, 20, 50 and 180 min) were determined in ten …