[HTML][HTML] Sensing stretch is fundamental

ND Epstein, JS Davis - Cell, 2003 - cell.com
ND Epstein, JS Davis
Cell, 2003cell.com
Stretch induces changes in cardiomyocyte biology that are implicated in heart failure, but the
mechanism by which stretch is sensed and signals are transduced is unknown. New
understanding of the Z disc elements of contractile units are beginning to elucidate the
mechanism of stretch sensing and its relation to cardiac adaptation and disease.
Abstract
Stretch induces changes in cardiomyocyte biology that are implicated in heart failure, but the mechanism by which stretch is sensed and signals are transduced is unknown. New understanding of the Z disc elements of contractile units are beginning to elucidate the mechanism of stretch sensing and its relation to cardiac adaptation and disease.
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