The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas
GF Pineo, E Regoeczi, MWC Hatton… - The Journal of …, 1973 - translationalres.com
Intravascular coagulation (thrombosis or defibrination) is frequently associated with mucin-
producing adenocarcinomas. Studies are reported which test the hypothesis that mucus
entering the circulation might activate coagulation and determine the site of activation.
Extracts of human mucus had procoagulant activity. Partial purification of the mucus extracts
was achieved and the product had remarkable stability, the procoagulant activity being
resistant to a variety of physicial conditions and chemical agents. The active material had a …
producing adenocarcinomas. Studies are reported which test the hypothesis that mucus
entering the circulation might activate coagulation and determine the site of activation.
Extracts of human mucus had procoagulant activity. Partial purification of the mucus extracts
was achieved and the product had remarkable stability, the procoagulant activity being
resistant to a variety of physicial conditions and chemical agents. The active material had a …
