Nitric oxide hemoglobin in patients receiving nitroglycerin as detected by electron paramagnetic resonance spectroscopy

LR Cantilena, RP Smith, S Frasur… - The Journal of …, 1992 - translationalres.com
Blood specimens were obtained from 30 adult patients admitted to a coronary care unit after
the decision to use nitroglycerin had been made by their physicians. The samples were
drawn before nitroglycerin administration, within 1 hour after starting nitroglycerin, after
several hours of therapy, and more than 4 hours after discontinuing therapy. One patient
was admitted twice, accounting for 31 sets of blood specimens. A positive identification of
nitric oxide-hemoglobin (NOHb), with electron paramagnetic resonance (EPR) spectroscopy …